pain in your arms or legs. Increased liver enzyme levels are a possible side effect of Zetia. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Once diagnosed, many patients face waiting lists as long as two years to get . Statins lower cholesterol by preventing your liver from making new cholesterol. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. Crestor is part of the statin drug class. Typical symptoms of POTS include: heart palpitations (feeling your heart beating or racing) dizziness or lightheadedness. stuffy nose. The dose of Zetia used for children is the same as the adult dose. Cholesterol absorption inhibitors prevent your small intestine from absorbing cholesterol. Zetia, Baclofen, and Xanax are not known to cause itching at all, but the Xanax can cause problems with memory which you do describe. Crestor contains the active drug rosuvastatin. The list below includes factors to consider. Created for people with ongoing healthcare needs but benefits everyone. Zetia and Lipitor have some similar side effects and others that vary. Like most drugs, Zetia can cause an allergic reaction in some people. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. Or they may recommend that you stop taking the medication. This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. Lipitor contains the active drug atorvastatin. Dr. said Zetia was different and would not cause these side effects, so I agreed to try it. Youll likely take Zetia once a day. During Zetia treatment, your doctor will likely recommend blood tests. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Zetia generally costs less than Lipitor. In studies, weight changes didnt occur in people who took the drug. Qu H, et al. It can develop suddenly or gradually over time. (2018). Leqvio is a prescription drug used to lower cholesterol. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. Physicians who treat dysautonomia can be located on our Physician List. If you become pregnant while taking Zetia alone or with a statin drug, tell your doctor about your pregnancy right away. It only comes in a strength of 10 milligrams (mg). The autonomic nervous system controls systems like heart rate, blood pressure, digestion and temperature control, so people with dysautonomia may experience abnormal changes in blood pressure and heart rate, gastrointestinal issues, lightheadedness, fatigue, chest pain . The primary symptom of OI is lightheadedness or fainting. Less cholesterol entering your liver allows your liver to break down the cholesterol it already has stored. Brand-name medications usually cost more than generics. In addition, you may need to watch out for grapefruit. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. In these studies, 12 weeks of treatment with Zetia and fenofibrate was compared with Zetia taken alone, fenofibrate taken alone, or a placebo (a treatment with no active drug). But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. Your doctor will likely start you on the typical dosage approved to treat your condition. Both drugs are typically taken once each day. For more information on the possible side effects of Zetia, talk with your doctor or pharmacist. Brand-name medications usually cost more than generics. Zetia is also used to reduce blood levels of fats called plant sterols in people with homozygous sitosterolemia. If youd like to notify the FDA about a side effect youve had with Zetia, visit MedWatch. But in studies, some people had to stop taking the drug due to feeling dizzy. It belongs to a class of drugs called cholesterol absorption inhibitors. The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. You should also look for supplements from reputable manufacturers. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. The Food and Drug Administration (FDA) approves prescription drugs such as Zetia to treat certain conditions. Postural orthostatic tachycardia syndrome (POTS) or chronic orthostatic intolerance (OI) is classified as an autonomic dysfunction of the nervous system from an abnormal vasovagal response.. At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Before starting a new medication, its a good idea to talk with a healthcare professional about any questions or concerns you may have. This active drug is also available as a generic medication. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Postural Tachycardia Syndrome (PoTS) is an abnormality of the autonomic nervous system (ANS). What are the serious side effects of Zetia? You may also have muscle cramps, spasms, or stiffness. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. Statins shouldnt be used during pregnancy. All rights reserved. More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. Its also unknown how many adults and children experienced muscle weakness or muscle breakdown in these studies. 4. Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. For more information on these side effects, see Side effect details below. Talk with your doctor to learn more about which medications are right for you. Statin drugs may pass into breast milk. The generic is considered to be as safe and effective as the original drug. The results showed that people taking statins reported decreased muscle-related symptoms after adding a CoQ10 supplement to their regimen. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. We've provided a list of the best at-home tests for. Currently, no medications have been approved by the FDA to treat POTS. Memory loss isnt a side effect of Zetia. In addition to Goff's specific symptoms, POTS can be associated with neurocognitive impairments or "brain fog"; problems with body temperature regulation; gastroenterological symptoms like nausea, abdominal pain, diarrhea, or constipation; and dark red-blue discoloration of the legs. When taken together, it should be administered at least 2 hours before or 4 hours after a bile acid sequestrant. After stopping Zetia treatment, their liver enzymes levels went back down. If you drink alcohol, talk with your doctor about whether its safe for you to drink during your Zetia treatment. For this purpose, Zetia may be used: The only FDA-approved dosage of Zetia is 10 mg once a day. It wasnt reported during studies of the drug. Last medically reviewed on September 18, 2021. Zetia is available in a generic form called ezetimibe. It isnt safe to eat grapefruit or drink grapefruit juice while using statins. Get answers to some frequently asked questions about Zetias side effects. Zetia generally costs more than Crestor. They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. Talk with your doctor if you have questions about managing your blood pressure or blood sugar while using Zetia. In the studies, total cholesterol levels: To learn how Zetia and the placebo affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Learn about side effects, dosage, and more. Here we look at how Zetia and Lipitor are alike and different. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. They often originate at the base of the skull and spreading on the back of the head and neck. What causes POTS? If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. You should always consult your doctor or another healthcare professional before taking any medication. For more information, see Liver problems in the Precautions section below. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). Zetia shouldnt cause weight gain or weight loss. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Zetia is approved to treat different types of high cholesterol. Is the ketogenic diet right for autoimmune conditions? Zetia may also be used off-label for other conditions. About Postural orthostatic tachycardia syndrome. Youll likely take it once a day. In addition, Zetia may be used with fenofibrate to treat mixed hyperlipidemia. And talk with your doctor if you have any questions about eating certain foods with Zetia. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. weakness and fatigue (tiredness) headaches. Study on Ezetimibe Yielded Disappointing Results: Another reader wrote us shortly after learning of the results of a study that raised questions about ezetimibe: Q. You may experience muscle problems as a side effect of Zetia. An allergic reaction is possible after using Zetia. Watch Part 2 here: https://youtu.be/HPfo2QOa89YHello Friends! Talk with your doctor if you have questions about using Zetia to lower your triglyceride levels. Additionally, a change in weight is not a listed side . Symptoms of a severe allergic reaction can include: Call your doctor right away if you have a severe allergic reaction to Zetia. Note: Some of the drugs listed here are used off-label to treat these specific conditions. For more information on these side effects, see Side effect details below. * For these purposes, Zetia and Crestor are used to treat people of different ages. If any of the following factors or conditions apply, you may have a higher risk of developing these muscle problems: If you have muscle-related side effects during Zetia treatment, talk with your doctor. You can use the study as a second opinion to make health care decisions. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. Zetia may not be right for you if you have certain medical conditions or other factors that affect your health. I am a stay at home mama to a sweet baby girl, and wife to an amazing h. If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. Your doctor may do liver function tests before you start treatment and regularly during your Zetia treatment. They can tell you about other medications that may work well for you. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. tightness of chest or wheezing. And your doctor can use this information to adjust your treatment plan if needed. LDL cholesterol was reduced by 15% more in children who took Zetia and simvastatin than in children who took simvastatin alone. fainting (passing out) problems with thinking, memory and concentration - this combination of symptoms is often called 'brain fog'. Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. This in turn increases clearance of cholesterol from the blood. Then you can share this information with your doctor. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. A malfunctioning ANS is sometimes called 'dysautonomia'. They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. Cholesterol is made naturally in your liver. dark colored urine. When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. But new medications can help lower cholesterol and improve heart health. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. (A class of drugs is a group of medications that work in a similar way.) yellowing of your skin or the whites of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to Statins for Lowering Cholesterol. If you develop increased liver enzyme levels, your doctor may make changes to your treatment plan. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia, or a malfunction of the autonomic nervous system. MS: Can the Mediterranean diet help preserve cognitive health? And some may be easily managed, too. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. 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